Dayquil – Uses, Side Effects And Dose


What Is DayQuil?

Dayquil is an over-the-counter (OTC) medicine that relieves flu and cold symptoms like pains, aches, nose congestion, cough, and sore throat. It contains three drugs comprising dextromethorphan, acetaminophen, and phenylephrine. This formula is often known as “DayQuil.”

It is available in a bottle of liquid and capsule form. Three hundred twenty-five milligrams of Acetaminophen and 10 milligrams of dextromethorphan are in each DayQuil tablet or capsule.


Each tablespoon has 5 mg of Phenylephrine. The liquid is taken orally in two tablespoons (30mL) every 4 hours. The recommended dosage for children and adults 12 or older is two capsules taken in a single dose every 4 hours.

How Does It Work?

It also eases pain and reduces temperature levels. Acetaminophen alleviates pain by altering the way your brain processes it. Also, it can interfere with your body’s natural thermostats. Further, the antitussive properties of dextromethorphan help reduce coughing. Phenylephrine, the third component, clears up stuffy noses.


Interactions with other medicines can be harmful. So, You don’t take this medication if you have used an MAO inhibitor in the previous 14 days. Linezolid, as well as isocarboxazid, are two examples that are MAO inhibitors.

Acetaminophen can be a trigger for liver damage and even death. Moreover, consult your doctor immediately if you feel diarrhoea, nausea, vomiting, severe headaches, or eyes that are yellow or irritated.

Also, it can trigger severe skin reactions in rare instances. Stop taking the medication if you notice redness on your skin, peeling, blistering, or redness.

Side Effects


There are a few side effects of DayQuil. These unintended effects aren’t enough to require a visit to a doctor. Once your body is used to the changes, the results may disappear. But, be sure to inquire about minor adverse side effects that bother you or won’t disappear with the help of your physician.

More Common Side Effects

Most complaints received from people who take DayQuil are:

  • Lightheadedness
  • Drool
  • stomach pain
  • nausea
  • vomiting
  • Nervousness
  • dizziness
  • Trouble sleeping

It can increase blood levels, so it is best to avoid grapefruit juice with it. Further, the higher doses can cause unwelcome reactions, including agitation and lightheadedness.

Serious Side Effects

Serious adverse side effects, such as allergic reactions, link with DayQuil. A list of the symptoms includes:

  • Rash
  • Hives
  • Itching
  • red, peeling, or blistering skin
  • Trouble breathing
  • Trouble swallowing
  • Swelling of lips, cheeks, tongue, and the throat

Also, stop DayQuil and seek medical assistance immediately if you experience adverse negative effects.

Dayquil Interactions

dayquil interaction

Acetaminophen is a practical choice for treating pain when combined with

  • Warfarin
  • isoniazid
  • Tegretol
  • phenobarbital
  • Phenytoin (Dilantin)

Dextromethorphan could interact with

  • Dextromethorphan could interact with
  • phenelzine (Nardil)
  • selegiline
  • Parnate

Doxylamine May Interact With:

  • isocarboxazid
  • phenelzine
  • selegiline
  • linezolid
  • Opioids like methadone, hydrocodone (fentanyl) hydrocodone, methadone, and
    morphine is readily available.

Talk With Your Doctor.

DayQuil can efficiently relieve a wide variety of flu and cold symptoms. The active ingredients help you feel better. But, the risk of adverse reactions is possible. DayQuil users should read the following information to ensure drug use correctly. Always consult your physician if you have any doubts.

What Are The Forms And Dosages?

LiquiCaps, the capsule form of DayQuil, contain a liquid filling. Also, it comes in a liquid drink that you consume. Dosage recommendations for each product, organized by age range, are provided below.

Typical Dosing For Dayquil


Capsules for oral use

  • The typical dose for people over 12 years old and up is two capsules every 4 hours. Don’t exceed eight capsules within 24 hours.

Oral tablets:  Acetaminophen 325mg, dextromethorphan 10mg, and phenylephrine 5mg are the specific quantities in each tablet.

  • The recommended dosage for adults and children over 12 years is two daily tablets.

Oral liquid:

  • For adults and children over 12 years, The recommended dosage is 30 millilitres (2 tablespoons) every four hours. Don’t exceed 120 millilitres (8 tablespoons) within a 24-hour time frame.
  • Children between 6 and 11 years old: The average dosage is 15 millilitres (1 tablespoon) in a single dose every 4 hours. Don’t exceed 60 millilitres (4 tablespoons) within a 24- hour time frame.
  • Children 3 years and younger: Don’t use it

Pros And Cons Of Dayquil


  • The combination of three medications is convenient for treating a variety of symptoms of flu and cold.
  • It starts working in 30 minutes.
  • It doesn’t cause drowsiness.
  • Generic available at a lower price.


  • Not recommended for use over a long time.
  • Not the most ideal option for those who drink a lot as it may increase the risk of liver damage.
  • Can raise blood pressure.

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